When you receive the Power glove and the Golden glove (Titan's Mitt), Link's hands turn either grey or gold. This is convenient for Alttp, but if you are using the custom Main Sprite, the grey and the gold colours will affect some other colour, which might be used for any part of the sprite, thus defecting it.

This fix will disable the additinal grey and gold colour to affect the main sprite (mandatory if your hack uses a custom main sprite):

PC (HEX) address on non-headered rom
0DEE24: change the default F0 to 80 (branch always).
(Address and new value found by Conn).